Course for international guest/part time students

Faculty

Faculty of Science

Organization

TTK Department of Organic Chemistry

Code

syntorgk20em

Title

Synthetic Organic Chemistry

Usual semester

Autumn

Published semester

2026/27/1

ECTS

4

Language

en

Learning outcomes

a) Knowledge - Students have structured knowledge in organic chemistry, which is sufficient to solve synthetic problems. They can use and understand up to date scientific literature. b) Abilities - Students are able to use their knowledge, in chemical research & development and innovation. They also can design experiments, analyze the obtained data and give valuable feedback and results for further developments. Students are able to identify the problems of their field of expertise, both in consultation with chemists and other scientific or technical professionals. Students are able to develop their technical language skills; they can communicate their ideas and results in Hungarian and in English. c) Attitude - Students handle their own and other’s achievements according to the ethical standards of his profession. Students are receptive to the use of new chemical technologies and environmental technologies. d) Autonomy and responsibility - Students are aware of the significance of his own professional statements and assumes the consequences of them. They responsibly operate chemical laboratory and chemical equipment, equipment.

Course content

1. Organic reactions – nucleophilicity, electrophilicity, drawing reaction mechanisms 2. Stereochemistry – theory of optical resolutions, determination of enantiomeric purity 3. Basicity, acidity, pKa, reaction rate, reaction mechanisms 4. Nucleophilic substitution reactions at saturated carbon atoms, elimination reactions, conformational analysis 5. Electrophilic addition reactions to alkenes and aromatic compounds 6. Reactions of carbonyl compounds, addition and nucleophilic substitution reactions on the carbonyl carbon 7. Delocalization and conjugation, conjugated addition and electrophilic aromatic substitution 8. Enols and enolates, synthesis and reactions, reactions of enolates with carbonyl compounds, Claisen type reactions 9. Carbenes, synthesis and reactions; neighboring group participation, rearrangements 10. Sulfur-containing compounds and their use in organic synthesis, phosphorous-containing compounds and their use in organic synthesis 11. Retrosynthetic analysis

Assessment method

Exam with written and oral parts, K(5).

Bibliography

J. Clayden, N. Greeves, S. Warren, Organic Chemistry (2nd ed., ) 2012, Oxford University Press S. Warren, P. Wyatt, Organic Synthesis – The Disconnection Approach (2nd ed.), 2008, John Wiley & Sons S. Warren, P. Wyatt, Workbook for Organic Synthesis – The Disconnection Approach (2nd ed.), 2009, John Wiley & Sons

Programmes of the course